**Are you an EPFL student looking for a semester project?**

Work with us on data science and visualisation projects, and deploy your project as an app on top of Graph Search.

Publication# Comparing connectomes across subjects and populations at different scales

Jean-Philippe Thiran, Stephan Morgenthaler, Alessandra Griffa, Elda Fischi Gomez, Patric Hagmann, Djalel Eddine Meskaldji

2013

Journal paper

2013

Journal paper

Abstract

Brain connectivity can be represented by a network that enables the comparison of the different patterns of struc- tural and functional connectivity among individuals. In the literature, two levels ofstatistical analysis have been con- sidered in comparing brain connectivity across groups and subjects: 1) the global comparison where a single measure that summarizes the information ofeach brain is used in a statistical test; 2) the local analysis where a sin- gle test is performed either for each node/connection which implies a multiplicity correction, or for each group of nodes/connections where each subset is summarized by one single test in order to reduce the number of tests to avoid a penalizing multiplicity correction. We comment on the different levels of analysis and present some methods that have been proposed at each scale. We highlight as well the possible factors that could influence the statistical results and the questions that have to be addressed in such an analysis

Official source

This page is automatically generated and may contain information that is not correct, complete, up-to-date, or relevant to your search query. The same applies to every other page on this website. Please make sure to verify the information with EPFL's official sources.

Related concepts (41)

Related publications (67)

Related MOOCs (13)

Ontological neighbourhood

A statistical hypothesis test is a method of statistical inference used to decide whether the data at hand sufficiently support a particular hypothesis. Hypothesis testing allows us to make probabilistic statements about population parameters. While hypothesis testing was popularized early in the 20th century, early forms were used in the 1700s. The first use is credited to John Arbuthnot (1710), followed by Pierre-Simon Laplace (1770s), in analyzing the human sex ratio at birth; see .

In statistical hypothesis testing, a result has statistical significance when a result at least as "extreme" would be very infrequent if the null hypothesis were true. More precisely, a study's defined significance level, denoted by , is the probability of the study rejecting the null hypothesis, given that the null hypothesis is true; and the p-value of a result, , is the probability of obtaining a result at least as extreme, given that the null hypothesis is true. The result is statistically significant, by the standards of the study, when .

In mathematics, a group action on a space is a group homomorphism of a given group into the group of transformations of the space. Similarly, a group action on a mathematical structure is a group homomorphism of a group into the automorphism group of the structure. It is said that the group acts on the space or structure. If a group acts on a structure, it will usually also act on objects built from that structure. For example, the group of Euclidean isometries acts on Euclidean space and also on the figures drawn in it.

Introduction to Geographic Information Systems (part 1)

Organisé en deux parties, ce cours présente les bases théoriques et pratiques des systèmes d’information géographique, ne nécessitant pas de connaissances préalables en informatique. En suivant cette

Introduction to Geographic Information Systems (part 1)

Organisé en deux parties, ce cours présente les bases théoriques et pratiques des systèmes d’information géographique, ne nécessitant pas de connaissances préalables en informatique. En suivant cette

Geographical Information Systems 1

Organisé en deux parties, ce cours présente les bases théoriques et pratiques des systèmes d’information géographique, ne nécessitant pas de connaissances préalables en informatique. En suivant cette

The arise of disagreement is an emergent phenomenon that can be observed within a growing social group and, beyond a certain threshold, can lead to group fragmentation. To better understand how disagreement emerges, we introduce an analytically tractable m ...

Victor Panaretos, Yoav Zemel, Valentina Masarotto

We consider the problem of comparing several samples of stochastic processes with respect to their second-order structure, and describing the main modes of variation in this second order structure, if present. These tasks can be seen as an Analysis of Vari ...

Daniel Patrick Collins, Subhadeep Banik, Willi Meier

A near collision attack against the Grain v1 stream cipher was proposed by Zhang et al. in Eurocrypt 18. The attack uses the fact that two internal states of the stream cipher with very low hamming distance between them, produce similar keystream sequences ...

2023